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Closed Clinical Trials

Our commitment to advancing breast cancer research has led us on a remarkable journey of discovery and innovation.

1200.89

Status:

Closed

Title:

Afatinib (BIBW2992) in HER2 (Human Epidermal Growth Factor Receptor 2)-Overexpressing Inflammatory Breast Cancer

Trial ID

 NCT01325428

A6181064, A6181107, A6181114

Status:

Closed

Title:

A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.

Trial ID

 NCT00428220

AMEERA-5

Status:

Closed

Title:

Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer (AMEERA-5)

Trial ID

 NCT04478266

AMG 386

Status:

Closed

Title:

Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients

Trial ID

 NCT00511459

AMG 706

Status:

Closed

Title:

An Open-label, Dose-finding Study to Evaluate the Safety of AMG 706 in Combination With Paclitaxel or Docetaxel as Treatment for Locally Recurrent or Metastatic Breast Cancer

Trial ID

 NCT00322400

ASLAN001-003

Status:

Closed

Title:

Randomized Phase 2A/2B Study to Compare the Efficacy and Safety of ASLAN001 + Capecitabine to Lapatinib + Capecitabine in Patients With HER 2-Positive MBC That Has Failed on Prior Trastuzumab Therapy

Trial ID

 NCT02338245

ATTAIN

Status:

Closed

Title:

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician’s Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Trial ID

 NCT02915744

B1891003

Status:

Closed

Title:

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

Trial ID

 NCT00777101

Bali-1

Status:

Closed

Title:

Cetuximab and Cisplatin in the Treatment of “Triple Negative” (Estrogen Receptor [ER] Negative, Progesterone Receptor [PgR] Negative, and Human Epidermal Growth Factor Receptor 2 [HER2] Negative) Metastatic Breast Cancer (BALI-1)

Trial ID

 NCT00463788

BAY 43-9006

Status:

Closed

Title:

A Phase III Randomized, Double Blind, Placebo-controlled Trial Comparing Capecitabine Plus Sorafenib Versus Capecitabine Plus Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast Cancer

Trial ID

 NCT01234337

BCIRG005

Status:

Closed

Title:

Docetaxel in Breast Cancer

Trial ID

 NCT00312208

BCIRG006

Status:

Closed

Title:

Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer

Trial ID

 NCT00021255

BEATRICE

Status:

Closed

Title:

A Study of Bevacizumab (Avastin) Adjuvant Therapy in Triple Negative Breast Cancer

Trial ID

 NCT00528567

Belle-2

Status:

Closed

Title:

Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor (BELLE-2)

Trial ID

 NCT01610284

Belle-4

Status:

Closed

Title:

A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation (BELLE-4)

Trial ID

 NCT01572727

BETH

Status:

Closed

Title:

Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab (BETH)

Trial ID

 NCT00625898

Big 1-98

Status:

Closed

Title:

Letrozole or Tamoxifen in Treating Postmenopausal Women With Breast Cancer (BIG 1-98)

Trial ID

 NCT00333775

BO17708

Status:

Closed

Title:

A Study of Bevacizumab (Avastin) in Women With HER2 Negative Metastatic Breast Cancer

Trial ID

 NCT00333775

BO20231

Status:

Closed

Title:

A Study of Avastin (Bevacizumab) in Combination With Herceptin (Trastuzumab)/Docetaxel in Patients With HER2 Positive Metastatic Breast Cancer.

Trial ID

 NCT00391092

CATS

Status:

Closed

Title:

Cardiotoxicity of Adjuvant Trastuzumab (CATS)

Trial ID

 NCT00858039

CBYL719A2201

Status:

Closed

Title:

Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women

Trial ID

 NCT01923168

CHARIOT

Status:

Closed

Title:

Patients with high-risk primary triple negative breast cancer who have had anthracycline-based chemotherapy will receive Ipilimumab and Nivolumab with weekly paclitaxel, followed by definitive surgery and further treatment with Nivolumab to evaluate the safety, feasibility and efficacy of this treatment.

Trial ID

 ACTRN12617000651381

CheckMate 7A8

Status:

Closed

Title:

A Study of Neoadjuvant Nivolumab + Palbociclib + Anastrozole in Post-Menopausal Women and Men With Primary Breast Cancer (CheckMate 7A8)

Trial ID

 NCT04075604

CLAG525B2101

Status:

Closed

Title:

A Study of Efficacy and Safety of LAG525 in Combination With Spartalizumab, or With Spartalizumab and Carboplatin, or With Carboplatin, in Patients With Advanced Triple-negative Breast Cancer

Trial ID

 NCT03499899

CLCL161A2201

Status:

Closed

Title:

A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With or Without LCL161 in Patients With Triple Negative Breast Cancer

Trial ID

 NCT01617668

CMCS110Z2201

Status:

Closed

Title:

Efficacy Study of MCS110 Given With Carboplatin and Gemcitabine in Advanced Triple Negative Breast Cancer (TNBC)

Trial ID

 NCT02435680

CONTESSA

Status:

Closed

Title:

Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/​MBC (CONTESSA)

Trial ID

 NCT03326674

D8480C00007

Status:

Closed

Title:

AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.

Trial ID

 NCT00454805

D-CARE

Status:

Closed

Title:

Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE)

Trial ID

 NCT01077154

ExteNET

Status:

Closed

Title:

Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer (ExteNET)

Trial ID

 NCT00878709

FACE

Status:

Closed

Title:

Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer (FACE)

Trial ID

 NCT00248170

Her2Climb

Status:

Closed

Title:

A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer (HER2CLIMB)

Trial ID

 NCT02614794

JPBO

Status:

Closed

Title:

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Trial ID

 NCT02308020

KEYNOTE-119

Status:

Closed

Title:

Study of Single Agent Pembrolizumab (MK-3475) Versus Single Agent Chemotherapy for Metastatic Triple Negative Breast Cancer (MK-3475-119/​KEYNOTE-119)

Trial ID

 NCT02555657

LUX-Breast 1

Status:

Closed

Title:

BIBW 2992 (Afatinib) in HER2-positive Metastatic Breast Cancer Patients After One Prior Herceptin Treatment

Trial ID

 NCT01125566

M12-895

Status:

Closed

Title:

A Randomized, Phase 2 Study of the Efficacy and Tolerability of Veliparib in Combination With Temozolomide or Veliparib in Combination With Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Subjects With BRCA1 or BRCA2 Mutation and Metastatic Breast Cancer

Trial ID

 NCT01506609

M12-914

Status:

Closed

Title:

A Phase 3 Randomized, Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the PARP Inhibitor Veliparib (ABT-888) in HER2-Negative Metastatic or Locally Advanced Unresectable BRCA-Associated Breast Cancer

Trial ID

 NCT02163694

monarcHER

Status:

Closed

Title:

A Study of Abemaciclib (LY2835219) in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer (monarcHER)

Trial ID

 NCT02675231

NEOSPHERE

Status:

Closed

Title:

A Study of Pertuzumab in Combination With Herceptin in Patients With HER2 Positive Breast Cancer.

Trial ID

 NCT00545688

PM0259 CA215BO

Status:

Closed

Title:

Phase II trial of oral Vinorelbine in combination with Capecitabine, and Trastuzumab as first line therapy in women with previously untreated HER2 positive metastatic breast cancer

PMC_TTAC-0001-05

Status:

Closed

Title:

TTAC-0001 and Pembrolizumab Phase Ib Combination Trial in Metastatic Triple-negative Breast Cancer

Trial ID

 NCT03720431

Puma_NER_6201

Status:

Closed

Title:

An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide

Trial ID

 NCT02400476

SBT6050

Status:

Closed

Title:

A Study of SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors

Trial ID

 NCT04460456

SHERsig

Status:

Closed

Title:

A Study of Herceptin (Trastuzumab)and Biomarkers in Patients With HER2-Positive Metastatic Breast Cancer

Trial ID

 NCT00885755

SOFT

Status:

Closed

Title:

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer (SOFT)

Trial ID

 NCT00066690

SPI-GCF-12-201

Status:

Closed

Title:

Phase 2 Study of SPI-2012 or Pegfilgrastim for the Management of Neutropenia in Participants With Breast Cancer

Trial ID

 NCT01724866

TCD11418

Status:

Closed

Title:

Study of SAR240550 (BSI-201) in Combination With Gemcitabine/​Carboplatin, in Patients With Metastatic Triple Negative Breast Cancer

Trial ID

 NCT01045304

TEACH

Status:

Closed

Title:

Tykerb Evaluation After Chemotherapy (TEACH): Lapatinib Versus Placebo In Women With Early-Stage Breast Cancer

Trial ID

 NCT00374322

TH3RESA

Status:

Closed

Title:

A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician’s Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy (TH3RESA)

Trial ID

 NCT01419197

TVEC_AMGEN

Status:

Closed

Title:

Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases

Trial ID

 NCT03256344

TyN

Status:

Closed

Title:

Lapatinib and vinorelbine in women with previously treated breast cancer

Trial ID

 ACTRN12610000347066

VEG108838

Status:

Closed

Title:

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast Cancer

Trial ID

 NCT00558103

More Information

For more information on clinical trials, get in contact with our Breast Clinical Trial Unit:

Breast Clinical Trials Unit (BCTU)

Business hours, Mon to Friday between 9am – 5pm

Email:  BCTU@bcrc-wa.com.au
Phone:  (08) 6500 5575

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